3-Chloro-1,1-Diethoxypropane

Diethoxypropane

Product Overview

    • 3-Chloro-1,1-Diethoxypropane, also known as 3-Chloropropionaldehyde Diethyl Acetal, is an exceptionally versatile bifunctional organic synthesis building block. It is commercially supplied as a clear, colorless to light yellow fluid liquid with a characteristic ether-like odor. ProCorBay International supplies premium synthesis-ready 3-Chloro-1,1-Diethoxypropane to chemical research teams, biotechnology lines, and active pharmaceutical laboratories requiring highly predictable reactivity metrics and ultra-low free acid matrices.
    • This compound is manufactured through the controlled hydrochlorination of acrolein setups in the presence of anhydrous ethanol, or via the selective chlorination of acrylaldehyde acetals under low-temperature controls, followed by multi-pass fractionated vacuum distillation to clear volatile ester fragments. ProCorBay manages strategic distribution lanes with premier specialty organohalogen complexes to supply material featuring high assays, regular boiling points, and minimal unreacted aldehyde variants.
    • In modern multi-step organic synthesis, this molecule serves as a powerful technical tool due to its distinct masked bifunctional layout. It features a reactive terminal alkyl chloride node coupled simultaneously with a protected diethyl acetal cluster. This unique architecture allows formulators to execute selective substitution reactions on the halogen node without attacking the sensitive carbonyl group, which can be unmasked via mild acid hydrolysis later in the pathway. It represents a vital synthesis route cornerstone for compounding advanced heterocyclic medications, specialized vitamins, and targeted neurological agents. ProCorBay handles steady bulk distributions to protect your automated processing schedules.

Applications

    • API Synthesis Intermediate: Crucial starter molecule utilized to build custom heterocyclic links and advanced generic medication side chains.
    • Specialty Agrochemicals: Key advanced intermediate employed in formulating target crop protection fungicides and active herbicides.

Benefits

    • Masked Bifunctional Layout: Protected acetal function prevents unwanted side reactions during aggressive basic substitutions.
    • High Chemical Assay: ≥ 98.0% minimum purity profile eliminates side-reaction risks inside industrial reactors.
    • Low Free Acidity Content: Strictly controlled tracking limits free hydrochloric acid components to stop premature acetal ring openings.
    • Excellent Organic Solubility: Mixes seamlessly with ethanol, ether, and acetone, optimizing batch cycle throughputs.
    • Predictable Distillation Quality: Consistent boiling boundaries ensure trouble-free processing in large industrial distillation columns.
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Frequently Asked Questions

The diethyl acetal group can be smoothly hydrolyzed into a reactive formyl aldehyde branch by adding a mild aqueous acid mixture during final processing steps.

No, it is immiscible in pure water. It must be processed inside anhydrous organic vehicles like ethanol or chloroform for clean setups.