Product Overview

• DL-Seryl Hydrazide Hydrochloride is a high-specialty amino acid derivative primarily utilized as an advanced intermediate in the manufacturing of targeted neurological therapies. Structurally composed of a serine amino acid backbone modified with a hydrazide functional group and stabilized as a hydrochloride salt, it is supplied as a white to off-white crystalline powder with high solubility in water and polar solvent systems. ProCorBay International supplies technical and characterization-ready DL-Seryl Hydrazide HCl to advanced API synthesis facilities requiring high structural validation, clean NMR profiles, and reliable reaction behavior.
• DL-Seryl Hydrazide HCl is manufactured through the precise esterification of DL-serine followed by hydrazinolysis using hydrazine hydrate under specialized temperature profiles. The resulting complex is carefully converted into its hydrochloride salt form to maximize stability and crystalline shelf life, followed by multiple recrystallization passes to eliminate trace hydrazine residues.
• Within the pharmaceutical industry, this molecule represents a critical raw block for generating antiparkinsonian agents and specific enzyme inhibitors—most notably serving as the key synthetic predecessor for Benserazide (a peripheral decarboxylase inhibitor used alongside Levodopa). Because impurities in hydrazide compounds can impact downstream pharmaceutical crystallization, ProCorBay manages strict analytical screening including verified NMR data, water content metrics, and heavy metal assays to ensure trouble-free integration into synthesis streams.