Product Overview

• Kopthione ZN 50% is a stabilized 50% aqueous dispersion of Zinc Pyrithione, a coordination complex formed between zinc and pyrithione ligands, widely recognized as one of the most effective broad-spectrum antimicrobial and antifungal actives used in personal care formulation. Chemically, Zinc Pyrithione is a zinc-chelated bis(2-pyridylthio) compound, supplied as a white to pale yellow, fine, free-flowing aqueous dispersion with a faint characteristic odor. It is insoluble in water in its pure crystalline state but is supplied by Procorbay as a stable, homogeneous 50% liquid dispersion for ease of dosing and incorporation into surfactant-based systems. Zinc Pyrithione exhibits potent activity against Malassezia (Pityrosporum ovale), the fungal species most closely associated with dandruff and seborrheic dermatitis, alongside broad antibacterial action. Procorbay International supplies Kopthione ZN 50% to shampoo, cosmetic, and industrial coatings manufacturers requiring a proven, regulatory-established antidandruff and preservative active with consistent particle size and dispersion stability.
• Zinc Pyrithione is manufactured through the reaction of sodium pyrithione with a zinc salt (typically zinc sulfate), forming an insoluble zinc-pyrithione complex that is subsequently milled to a controlled fine particle size and stabilized as an aqueous dispersion to prevent agglomeration and ensure consistent bioactivity. Procorbay sources Kopthione ZN 50% from established antimicrobial ingredient manufacturers with validated quality control over particle size distribution, active content, and microbial/heavy metal impurity limits.
• Zinc Pyrithione has been the gold-standard active ingredient in antidandruff shampoo formulations for over five decades, valued for its dual antifungal and antibacterial mechanism of action, which disrupts microbial membrane transport and metal-dependent enzymatic processes. Beyond haircare, it is incorporated into medicated skin creams, soaps, and acne-care formulations for its antiseptic properties, and finds significant industrial application as a marine antifouling agent in paints and coatings, as well as a preservative in adhesives, sealants, and leather-processing formulations where fungal and bacterial growth control is required.
• Given its status as a globally regulated cosmetic active (subject to concentration limits in leave-on and rinse-off products under most major cosmetic regulatory frameworks), Procorbay maintains a dependable, quality-documented supply of Kopthione ZN 50% to support formulators who require both regulatory compliance data and consistent dispersion performance across production batches.