N-(4-Hydroxyphenyl)Acetamide

Acetamide

Product Overview

    • N-(4-Hydroxyphenyl)Acetamide, known globally across the medical and retail industries as Paracetamol or Acetaminophen, is a premier synthetic non-opioid analgesic and antipyretic active ingredient. Chemically, it consists of a core benzene ring substituted with a hydroxyl group and an acetamido functional stream fixed at para positions. It is commercially supplied as a brilliant white, odorless crystalline powder featuring a slightly bitter taste profile. ProCorBay International directs massive industrial bulk logistics lines of premium, pharmacopoeial-grade Paracetamol to high-capacity medicine formulators, generic tablet factories, and syrup bottling plants worldwide.
    • Paracetamol is manufactured through the industrial nitration of phenol to yield 4-nitrophenol, followed by reduction to 4-aminophenol and subsequent crisp acetylation using high-purity acetic anhydride matrices. ProCorBay coordinates strategic supply tracks exclusively with world-class, GMP-certified chemical manufacturing complexes to deliver granules featuring ultra-low 4-aminophenol impurity thresholds, zero heavy metal traces, and exceptional structural stability.
    • Within the modern global healthcare ecosystem, this compound is one of the most widely deployed over-the-counter (OTC) active pharmaceutical ingredients. Mechanistically, it acts primarily by inhibiting prostaglandin synthesis within the central nervous system, effectively blocking pain signaling paths and lowering fever profiles safely via the hypothalamic heat-regulating center. Because it exhibits excellent gastrointestinal tolerability and lacks aggressive anti-platelet side effects, it is universally trusted across adult and pediatric formulation configurations. ProCorBay handles deep, multi-ton inventory lines to guarantee pricing safety and smooth production continuity for leading global consumer health brands.

Applications

    • Pharmaceutical Formulation: Core active raw input utilized to manufacture finished oral solid tablets, effervescent discs, and fast-melt capsules.
    • Liquid Oral Dosages: Main therapeutic ingredient in pediatric analgesic drops, liquid cough-and-cold syrups, and oral suspensions.
    • Combination Remedies: Co-formulated alongside caffeine, codeine, or decongestants for advanced multi-symptom cold relief products.

Benefits

    •  
    • High Tissue Safety: Demonstrates excellent stomach lining compatibility compared to typical NSAID configurations.
    • Optimized Granulometry: Available in varied powder or direct-compression (DC) granular formats to fit high-speed tableting machinery.
    • Pharmacopoeial Benchmark: Strictly matches international USP, EP, BP, and IP regulatory monographs across all distribution lots.
    • Rapid Thermal Stabilization: Low level of volatile residues ensures highly predictable compounding performance in large factory blenders.
    • Exceptional Clean Assay: ≥ 99.5% active purity minimizes processing catalyst residues.

REQUEST INFORMATION

Note : If you do not receive the confirmation message within a few minutes of submitting this form then please check your Spam or Bulk E-mail folder.

CONTACT OUR REPRESENTATIVE

Related Products

Fluorocytosine
Pharmaceutical

5-Fluorocytosine

5-Fluorocytosine, known across medical and regulatory frameworks by its g...

Diphosphonic
Pharmaceutical

4-Amino-1,1-Diphosphonic Acid

4-Amino-1,1-Diphosphonic Acid, widely identified across international act...

Fluoro
Pharmaceutical

1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-7-(1-Piperazinyl)- Quinoline Intermediate

1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-7-(1-Piperazinyl)- Quinoline Interme...

Pheny
Pharmaceutical

Phenyl-(2-Pyridyl)-Aceto Nitrile

Phenyl-(2-Pyridyl)-Aceto Nitrile is an advanced substituted acetonitrile arom...

Frequently Asked Questions

Standard powder requires wet granulation processing before compression, while DC grades are engineered with excipients to feed directly into tableting machines.

4-aminophenol is the primary degradation byproduct and synthesis residue; maintaining it at ultra-low parts-per-million (ppm) prevents toxicity issues.