Product Overview

• (S)-(+)-N-(2,3-Epoxypropyl)Phthalimide, also known as (S)-Glycidyl Phthalimide, is an exceptionally high-tier chiral heterocyclic building block compound. It is commercially supplied as an off-white to white crystalline powder or fine needles. ProCorBay International supplies highly refined, high-chiral purity (S)-(+)-N-(2,3-Epoxypropyl)Phthalimide to active pharmaceutical ingredient laboratories and premium generic synthesis plants requiring strict, high-precision stereochemical controls.
• This compound is manufactured through the stereospecific nucleophilic substitution reaction connecting pure potassium phthalimide matrices with optically active (R)-epichlorohydrin or related chiral oxirane pathways, followed by multiple low-temperature crystallization passes to eliminate trace enantiomeric impurities. ProCorBay forces quality audits strictly through advanced specialty biochemical lines featuring high optical rotation data and minimal heavy metal variables.
• Within advanced modern healthcare manufacturing, this epoxidized phthalimide represents a vital chiral core synthesis piece. It functions as the direct chiral starting material and regulatory predecessor for compounding modern oxazolidinone-class oral anticoagulants—most notably serving as the key synthetic block for Rivaroxaban. The localized oxirane epoxy ring provides a highly active node for regioselective ring-opening reactions, helping developers fix the mandatory (S)-configuration into final blood-thinning drug profiles. ProCorBay provides complete analytical validation records to ensure seamless compliance trails.